I'm stupid, but i need to ask..

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I'm sorry for being stupid, but i need to ask.. Before i do, i just wanna say that i did finish AAMFP, twice, trying to read every note.. But i still don't get it!

Spoiler below!

Oswald Mandus returns from a disasterous expedition in Mexico, and wakes up in fever.. What did he discover there, as he says "Yes.. I seem to have picked up something rather nasty in Mexico" Must have missed something..

He is the one who created the machine? Is it the machine that talks the entire gameplay, even calls you along the gameplay?

Also, he slaughters humans, who then turns in to pigs? On Steam is says that the game contain one of the darkest, most horrific storys ever told in a game.. ?

Yet again, extremly sorry for my questions, feel so stupid, almost didn't want to post this, but i wanted to know so bad!

Spoiler below!

Although he, indeed, literally picked up something in Mexico, this response was rather another way of saying: "I got sick".

Yes, he had created the machine. About, whether it is the machine speaking or not, it's still an unknown.

At first he slaughtered only pigs, then humans, only later he'd discovered that re-shaping humans and pigs into one being is possible, so he used some of the "products" for this conversion.